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1182027 Post Posted: Mon Jan 09, 2012 8:51 pm Thank this member for this postReply with quote Add User to Ignore List Back To Top

Rosbotham  


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Similar too. My HbA1C had got to 7.1...not quite time for tablets but getting there. Got rid of 4 stone, now running at 5.4. Now merely overweight rather than obese. Blood pressure tablets reduced to a quarter of what they were as I kept getting dizzy on the old dose (anyone "normal" wouldn't be on them at all; my BP is managed low to protect my kidney...balancing act of as low as possible without me keeling over).

I'm puzzled by Ken's post...my understanding of the difference of Type 1 vs Type 2 is around whether the pancreas is incapable of creating insulin (1) or doesn't create sufficient/body doesn't process it well (2). I didn't think you went from Type 2 to 1, let alone miraculously subsequently be ok - once you've got Type 1 that's it. I wonder whether it's the popular misconception that 1=insulin dependent, 2=tablet/diet...while Type 1 people are insulin dependent you can be Type 2 and on insulin as well. Hopefully one of the medics on here will confirm me right or wrong.
 
1182063 Post Posted: Mon Jan 09, 2012 9:32 pm Thank this member for this postReply with quote Add User to Ignore List Back To Top

wakk44 Linked Subscriber 21/09/2015 


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I don't think that type 2 can develop into type 1.The majority of type 1 cases are diagnosed at a young age,sometimes in childhood and it is when the body produces very little or no insulin at all.

Type 2 is usually diagnosed later in life and is when the body can't produce enough insulin or develops insulin resistance affecting the breakdown of sugar in the bloodstream.
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explains it a bit better than I can.

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cheers Steve Signhi wave
 
1182097 Post Posted: Mon Jan 09, 2012 9:57 pm Thank this member for this postReply with quote Add User to Ignore List Back To Top

SaddleTramp  


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That is not according to the NHS an exact description

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What is type 2 diabetes?

Type 2 diabetes occurs when not enough insulin is produced by the body for it to function properly, or when the body’s cells do not react to insulin. This is called insulin resistance.
Type 2 diabetes is far more common than type 1 diabetes, which occurs when the body does not produce any insulin at all. Around 90% of all adults in the UK with diabetes have type 2 diabetes.
If you have type 2 diabetes, you may be able to control your symptoms simply by eating a healthy diet and monitoring your blood glucose level. However, as type 2 diabetes is a progressive condition, you may eventually need to take insulin medication, usually in the form of tablets.
Type 2 diabetes is often associated with obesity. Obesity-related diabetes is sometimes referred to as maturity-onset diabetes because it is more common in older people.

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What is type 1 diabetes?

Type 1 diabetes occurs when the body produces no insulin. It is often referred to as insulin-dependent diabetes. It is also sometimes known as juvenile diabetes or early-onset diabetes because it usually develops before the age of 40, often during the teenage years.
Type 1 diabetes is far less common than type 2 diabetes, which occurs when the body produces too little insulin or when the cells in the body do not react properly to insulin. People with type 1 diabetes make up only 10% of all people with diabetes.
If you have type 1 diabetes, you will need to take insulin injections for life. You must also make sure that your blood glucose levels stay balanced by eating a healthy diet and carrying out regular blood tests.

As far as the NHS is concerned Type 1 is injection controlled when tablets cannot control it.
Type 2 is when Tablets or diet can control it.

An extremely good friend of mine had no sign of diabetes until 52 y/o then developed Type 2, after an extremely short period of time he was Diagnosed as type 1, He is now disabled and he is still only 55 yo.

Some doctors actually confirm how your link describes the difference yet others don't, Which is true ?? I have no idea but I know how my doctor describes it. Very Happy
 
1182103 Post Posted: Mon Jan 09, 2012 10:06 pm Thank this member for this postReply with quote Add User to Ignore List Back To Top

Rosbotham  


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"Starting insulin injections does not mean that you have now developed Type 1 diabetes. You still have Type 2 diabetes but it is treated with insulin."

My wife was Type 2, treated by insulin.
 
1182122 Post Posted: Mon Jan 09, 2012 10:37 pm Thank this member for this postReply with quote Add User to Ignore List Back To Top

Penquin Linked Subscriber 10/01/2015 


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Type 1 is due to the body not producing insulin - there are various reasons for this including an autoimmune reaction, and a possible viral infection.

The Beta cells of the Islets of Langerhans in the pancreas are very sensitive and can stop producing insulin for a variety of reasons, but the outcome is the same - the inability of the body to convert glucose to glycogen for storage. This means that glucose levels rise in the blood above 110mg/100cm3 of blood - at that level the kidney tubules are unable to reabsorb all of the glucose from the "urine" as it is being produced and so urine contains glucose - hence the old name "sugar diabetes" - the Doctor used to test by tasting the urine - if it was sweet the diagnosis was confirmed.

Failure to produce insulin resulted in the body losing all of the glucose it obtained so it switches to using fat as a reseve to start with, followed by protein as a food reserve - so weight loss is dramatic and very rapid and the body's thirst is amazing - "hell hath no thirst like a diabetic deprived of insulin" - they fill their stomach with water and are STILL thirsty.

This is treated by injections of insulin - developed by two Canadian researchers in the 1920's - Banting and Best, they identified the hormone and it's role and worked out how to extract insulin from pancreases of dead animals. This was used until the mid 1980's using insulin derived from pigs or cattle carcases. BUT the insulin was not ideal and much did not work due to the body rejecting it.

In the ate 1970's and early 1980's it was discovered how to genetically engineer a bacterium (Escherichia coli) to make insulin identical to human insulin. Gradually more insulin type drugs have been synthesised which work even better.

That is used for Type 1 (Insulin Dependent Diabetes) and the process is irreversible, once on insulin you stay on insulin as the pancreas cells involved pack up permanently.

There are trials taking place at present using Beta cells transferred from others - but the rejection remains a problem. There are also research trials using the cells of the person involved and splicing in the working gene - still at the research level.

Type 2 is where the person does not produce enough insulin or the body does not respond as it should - this is commonly linked to obesity where the bodies needs are greater than the insulin can supply so the body cannot use the glucose and excretes it. Type 2 is normally treated initially with tablets to increase insulin production, if that fails then some insulin therapy ma be needed to supplement - this can be reduced if/when the obesity problem is solved.

All of this is standard A level Biology teaching - coupled with me being a great friend of the principle research team leader in Exeter (a father of one of my former students Laughing ) so this information is current and accurate.

Hope it helps you to understand, currently 2% of the UK population are KNOWN to be diabetic and an estimated further 2% are also but have not yet been confirmed or identified.

Dave
 
1182175 Post Posted: Tue Jan 10, 2012 12:09 am Thank this member for this postReply with quote Add User to Ignore List Back To Top

rugbyken Subscriber 25/04/2015 


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there are a couple in the family with type 1 diabetes and your all correct it was just lazy to say mum was type 1 when i should have said insulin dependent type 2 but to the layman that tends to be the criterea differential .
if your all getting such good results with the weight loss looks like no hiding place damn i do love my food & my beer & my red wine and sugar in my tea but ????
 
1182230 Post Posted: Tue Jan 10, 2012 8:59 am Thank this member for this postReply with quote Add User to Ignore List Back To Top

bigbazza Subscriber 21/03/2015 


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Very Happy Very Happy Very Happy

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Barry

Keep fighting with Melvis Bazooka
 
1182245 Post Posted: Tue Jan 10, 2012 9:26 am Thank this member for this postReply with quote Add User to Ignore List Back To Top

Rosbotham  


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rugbyken wrote:

if your all getting such good results with the weight loss looks like no hiding place damn i do love my food & my beer & my red wine and sugar in my tea but ????


20 mins / 10km on exercise bike = 200 calories = 1 pint of beer.

I don't exercise to keep fit, I exercise so I can eat/drink more. Laughing
 
1182377 Post Posted: Tue Jan 10, 2012 12:53 pm Thank this member for this postReply with quote Add User to Ignore List Back To Top

stewartwebr Subscriber 17/02/2015 


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SaddleTramp wrote:
4 months ago after my regular blood test Doc told me he was going to put me on insulin injections as I was on Max tablets possible, I didn't want that at any cost, He had warned me the month before that if things kept on what he was going to do.
I had already decided to diet and had actually just started the diet, so he said Ok we will re test in 3 months (Dec) and see what happens.
I lost just over a stone after 5 weeks and had already had to phone him as I was nearly hypoing out, he knocked a tablet of and I carried on, after 2 months I had lost almost 2 stone and had another tablet knocked off which was in fact the most powerful one I was taking, at 3 months I had lost 2 1/2 stone I am now on my way to 3 stones lost and and had 2 more tablets knocked off.
The difference I feel is astronomical, I now go to the gym most days, Not to get muscles but to get rid of some of the excess flab I have, My waist has gone from 44ins and I am now at 36ins, Instead of 3X shirts etc I am now down to XL and I have now regained all my self confidence.

How wonderful life is. Very Happy Very Happy Very Happy


Well done Les, what a great achievement. It's not easy but you are seeing the benefits...congratulations...keep it up Wink
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